Endocrine Abstracts

Introduction: Some physiological changes in HbA1c during pregnancy should be considered to determine its optimal value for glycemic control. Erythrocytes half-life decreases during pregnancy, which is reflected in a decrease in HbA1c.Aim: The aim of this study is to analyse HbA1c during pregnancy in healthy population of pregnant woman. Matherial and methods: The study included 77 pregnant women in the first trimester registered in Center for endocrinolo...

Introduction: The basic characteristics of metabolism in pregnancy are changes from anabolic to catabolic conditions with an increase in insulin resistance, moderate, reversible increase in lipid concentration in the blood, and accumulation of fat stores in the mother’s tissues. Lipid metabolism is essential for the development of healthy pregnancy, and fatty acids are a significant source of energy and a key element for membrane synthesis, while cholesterol, in addition ...

Introduction: The basic characteristics of metabolism in pregnancy are changes from anabolic to catabolic conditions. During early gestation, the fetus is dependent on maternal thyroid hormones that cross the placenta. Thyroid disease in pregnancy is a common clinical problem, at least 2–3% of women have thyroid dysfunction. Pre-conceptual education and appropriate diagnosis and treatment of thyroid dysfunction in early pregnancy are of great importance, with the aim of ...

Introduction: Thyroid disease in pregnancy is a common clinical problem, at least 2–3% of women have thyroid dysfunction, and it is estimated that about 5–20% of women of reproductive age suffer from autoimmune thyroid disease. Subclinical thyroid disease during pregnancy may be associated with adverse outcomes. In the first trimester, the ‘normal’ range for TSH is reduced to 0.1–2.5 mIU/l, and in the second and third trimester is 3.0 mIU/l.<p clas...

Introduction: Pregnancy as a state of insulin resistance can predict diabetes development in some women, and is associated with increased risk for adverse outcome of neonate and for mother.Aim: The aim of this study is to analyse pregnancy outcome in relation to a disorder of glucose tolerance during pregnancy.Matherial and methods: The study included 77 healthy pregnant women in third trimester registered in Center for endocrinolo...